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N-Benzyl substitution of polyhydroxypyrrolidines - the way to selective inhibitors of Golgi α-mannosidase II
Inhibition of biosynthesis of complex N-glycans in Golgi apparatus influence progress of tumor growth and metastasis. Golgi α-mannosidase II (GMII) has become a therapeutic target for a drug with anticancer activities. One critical task for successful application GMII drugs in medicine treatment is...
Kaydedildi:
| Yayımlandı: | ChemMedChem |
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| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176901/ https://ncbi.nlm.nih.gov/pubmed/29323461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201700607 |
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