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Molecular mechanisms of the interhead coordination by interhead tension in cytoplasmic dyneins

Cytoplasmic dyneins play a major role in retrograde cellular transport by moving vesicles and organelles along microtubule filaments. Dyneins are multidomain motor proteins with two heads that coordinate their motion via their interhead tension. Compared with the leading head, the trailing head has...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Qian, Jana, Biman, Diehl, Michael R., Cheung, Margaret S., Kolomeisky, Anatoly B., Onuchic, José N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176594/
https://ncbi.nlm.nih.gov/pubmed/30224489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806688115
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