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Molecular mechanisms of the interhead coordination by interhead tension in cytoplasmic dyneins
Cytoplasmic dyneins play a major role in retrograde cellular transport by moving vesicles and organelles along microtubule filaments. Dyneins are multidomain motor proteins with two heads that coordinate their motion via their interhead tension. Compared with the leading head, the trailing head has...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176594/ https://ncbi.nlm.nih.gov/pubmed/30224489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806688115 |
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