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Molecular mechanisms of the interhead coordination by interhead tension in cytoplasmic dyneins

Cytoplasmic dyneins play a major role in retrograde cellular transport by moving vesicles and organelles along microtubule filaments. Dyneins are multidomain motor proteins with two heads that coordinate their motion via their interhead tension. Compared with the leading head, the trailing head has...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Wang, Qian, Jana, Biman, Diehl, Michael R., Cheung, Margaret S., Kolomeisky, Anatoly B., Onuchic, José N.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176594/
https://ncbi.nlm.nih.gov/pubmed/30224489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806688115
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