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DNMTs inhibitor SGI-1027 induces apoptosis in Huh7 human hepatocellular carcinoma cells
SGI-1027, a novel class of relatively stable, highly lipophilic quinoline-based small-molecule inhibitors of DNA methyltransferase enzymes (DNMTs), is able to inhibit DNMTs activity, and reactivate tumor suppressor genes. However, the potential anticancer mechanisms of SGI-1027 on human hepatocellul...
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| Publicado no: | Oncol Lett |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176375/ https://ncbi.nlm.nih.gov/pubmed/30344731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9390 |
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