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Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling

Glucocorticoid excess induces apoptosis of islet cells, which may result in diabetes. In this study, we investigated the protective effect of ghrelin on dexamethasone-induced INS-1 cell apoptosis. Our data showed that ghrelin (0.1 μM) inhibited dexamethasone-induced (0.1 μM) apoptosis of INS-1 cells...

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Détails bibliographiques
Publié dans:Int J Endocrinol
Auteurs principaux: Zhang, Chengshuo, Li, Le, Zhao, Bochao, Jiao, Ao, Li, Xin, Sun, Ning, Zhang, Jialin
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844876/
https://ncbi.nlm.nih.gov/pubmed/27190513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4513051
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