Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling

Glucocorticoid excess induces apoptosis of islet cells, which may result in diabetes. In this study, we investigated the protective effect of ghrelin on dexamethasone-induced INS-1 cell apoptosis. Our data showed that ghrelin (0.1 μM) inhibited dexamethasone-induced (0.1 μM) apoptosis of INS-1 cells...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Endocrinol
Hauptverfasser: Zhang, Chengshuo, Li, Le, Zhao, Bochao, Jiao, Ao, Li, Xin, Sun, Ning, Zhang, Jialin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844876/
https://ncbi.nlm.nih.gov/pubmed/27190513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4513051
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