Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling

Glucocorticoid excess induces apoptosis of islet cells, which may result in diabetes. In this study, we investigated the protective effect of ghrelin on dexamethasone-induced INS-1 cell apoptosis. Our data showed that ghrelin (0.1 μM) inhibited dexamethasone-induced (0.1 μM) apoptosis of INS-1 cells...

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Detalhes bibliográficos
Publicado no:Int J Endocrinol
Main Authors: Zhang, Chengshuo, Li, Le, Zhao, Bochao, Jiao, Ao, Li, Xin, Sun, Ning, Zhang, Jialin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844876/
https://ncbi.nlm.nih.gov/pubmed/27190513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4513051
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