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Modulation of proteoglycan receptor PTPσ enhances MMP-2 activity to promote recovery from multiple sclerosis

Multiple Sclerosis (MS) is characterized by focal CNS inflammation leading to the death of oligodendrocytes (OLs) with subsequent demyelination, neuronal degeneration, and severe functional deficits. Inhibitory chondroitin sulfate proteoglycans (CSPGs) are increased in the extracellular matrix in th...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Luo, Fucheng, Tran, Amanda Phuong, Xin, Li, Sanapala, Chandrika, Lang, Bradley T., Silver, Jerry, Yang, Yan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175851/
https://ncbi.nlm.nih.gov/pubmed/30297691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06505-6
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