Enhanced regeneration and functional recovery after spinal root avulsion by manipulation of the proteoglycan receptor PTPσ

Following root avulsion, spinal nerves are physically disconnected from the spinal cord. Severe motoneuron death and inefficient axon regeneration often result in devastating motor dysfunction. Newly formed axons need to extend through inhibitory scar tissue at the CNS-PNS transitional zone before e...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Li, Heng, Wong, Connie, Li, Wen, Ruven, Carolin, He, Liumin, Wu, Xiaoli, Lang, Bradley T., Silver, Jerry, Wu, Wutian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604492/
https://ncbi.nlm.nih.gov/pubmed/26464223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14923
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