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Enhanced regeneration and functional recovery after spinal root avulsion by manipulation of the proteoglycan receptor PTPσ

Following root avulsion, spinal nerves are physically disconnected from the spinal cord. Severe motoneuron death and inefficient axon regeneration often result in devastating motor dysfunction. Newly formed axons need to extend through inhibitory scar tissue at the CNS-PNS transitional zone before e...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Li, Heng, Wong, Connie, Li, Wen, Ruven, Carolin, He, Liumin, Wu, Xiaoli, Lang, Bradley T., Silver, Jerry, Wu, Wutian
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604492/
https://ncbi.nlm.nih.gov/pubmed/26464223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14923
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