Perturbing chondroitin sulfate proteoglycan signaling through LAR and PTPσ receptors promotes a beneficial inflammatory response following spinal cord injury

BACKGROUND: Traumatic spinal cord injury (SCI) results in upregulation of chondroitin sulfate proteoglycans (CSPGs) by reactive glia that impedes repair and regeneration in the spinal cord. Degradation of CSPGs is known to be beneficial in promoting endogenous repair mechanisms including axonal spro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neuroinflammation
Prif Awduron: Dyck, Scott, Kataria, Hardeep, Alizadeh, Arsalan, Santhosh, Kallivalappil T., Lang, Bradley, Silver, Jerry, Karimi-Abdolrezaee, Soheila
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861616/
https://ncbi.nlm.nih.gov/pubmed/29558941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1128-2
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