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Enhanced regeneration and functional recovery after spinal root avulsion by manipulation of the proteoglycan receptor PTPσ

Following root avulsion, spinal nerves are physically disconnected from the spinal cord. Severe motoneuron death and inefficient axon regeneration often result in devastating motor dysfunction. Newly formed axons need to extend through inhibitory scar tissue at the CNS-PNS transitional zone before e...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Heng, Wong, Connie, Li, Wen, Ruven, Carolin, He, Liumin, Wu, Xiaoli, Lang, Bradley T., Silver, Jerry, Wu, Wutian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604492/
https://ncbi.nlm.nih.gov/pubmed/26464223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14923
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