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Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Psychiatric disorders are thought to have a complex genetic pathology consisting of interplay of common and rare variation. Traditionally, pedigrees are used to shed light on the latter only, while here we discuss the application of polygenic risk scores to also highlight patterns of common genetic...

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書誌詳細
出版年:Commun Biol
主要な著者: de Jong, Simone, Diniz, Mateus Jose Abdalla, Saloma, Andiara, Gadelha, Ary, Santoro, Marcos L., Ota, Vanessa K., Noto, Cristiano, Curtis, Charles, Newhouse, Stephen J., Patel, Hamel, Hall, Lynsey S., O`Reilly, Paul F., Belangero, Sintia I., Bressan, Rodrigo A., Breen, Gerome
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175827/
https://ncbi.nlm.nih.gov/pubmed/30320231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0155-y
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