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Polygenic risk score analyses of symptoms and treatment response in an antipsychotic-naive first episode of psychosis cohort

In this study, we aimed to test if the schizophrenia (SCZ) polygenic risk score (PRS) was associated with clinical symptoms in (a) the first episode of psychosis pre-treatment (FEP), (b) at nine weeks after initiation of risperidone treatment (FEP-9W) and (c) with the response to risperidone. We per...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Santoro, Marcos Leite, Ota, Vanessa, de Jong, Simone, Noto, Cristiano, Spindola, Leticia M., Talarico, Fernanda, Gouvea, Eduardo, Lee, Sang Hyuck, Moretti, Patricia, Curtis, Charles, Patel, Hamel, Newhouse, Stephen, Carvalho, Carolina Muniz, Gadelha, Ary, Cordeiro, Quirino, Bressan, Rodrigo Affonseca, Belangero, Sintia Iole, Breen, Gerome
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119191/
https://ncbi.nlm.nih.gov/pubmed/30171181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0230-7
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