Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Psychiatric disorders are thought to have a complex genetic pathology consisting of interplay of common and rare variation. Traditionally, pedigrees are used to shed light on the latter only, while here we discuss the application of polygenic risk scores to also highlight patterns of common genetic...

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Bibliographic Details
Published in:Commun Biol
Main Authors: de Jong, Simone, Diniz, Mateus Jose Abdalla, Saloma, Andiara, Gadelha, Ary, Santoro, Marcos L., Ota, Vanessa K., Noto, Cristiano, Curtis, Charles, Newhouse, Stephen J., Patel, Hamel, Hall, Lynsey S., O`Reilly, Paul F., Belangero, Sintia I., Bressan, Rodrigo A., Breen, Gerome
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175827/
https://ncbi.nlm.nih.gov/pubmed/30320231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0155-y
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