Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Psychiatric disorders are thought to have a complex genetic pathology consisting of interplay of common and rare variation. Traditionally, pedigrees are used to shed light on the latter only, while here we discuss the application of polygenic risk scores to also highlight patterns of common genetic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Commun Biol
Prif Awduron: de Jong, Simone, Diniz, Mateus Jose Abdalla, Saloma, Andiara, Gadelha, Ary, Santoro, Marcos L., Ota, Vanessa K., Noto, Cristiano, Curtis, Charles, Newhouse, Stephen J., Patel, Hamel, Hall, Lynsey S., O`Reilly, Paul F., Belangero, Sintia I., Bressan, Rodrigo A., Breen, Gerome
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175827/
https://ncbi.nlm.nih.gov/pubmed/30320231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0155-y
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