Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of parkinsonian rats

Dopamine (DA) neurons derived from human embryonic stem cells (hESCs) are a promising unlimited source of cells for cell replacement therapy in Parkinson's disease (PD). A number of studies have demonstrated functionality of DA neurons originating from hESCs when grafted to the striatum of rode...

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Bibliographic Details
Published in:J Comp Neurol
Main Authors: Cardoso, Tiago, Adler, Andrew F., Mattsson, Bengt, Hoban, Deirdre B., Nolbrant, Sara, Wahlestedt, Jenny Nelander, Kirkeby, Agnete, Grealish, Shane, Björklund, Anders, Parmar, Malin
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Inc. 2018
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175216/
https://ncbi.nlm.nih.gov/pubmed/30007046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.24500
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