Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease

Stem cell treatments for neurodegenerative diseases are expected to reach clinical trials soon. Most of the approaches currently under development involve transplantation of immature progenitors that subsequently undergo phenotypic and functional maturation in vivo, and predicting the long-term graf...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Kirkeby, Agnete, Nolbrant, Sara, Tiklova, Katarina, Heuer, Andreas, Kee, Nigel, Cardoso, Tiago, Ottosson, Daniella Rylander, Lelos, Mariah J., Rifes, Pedro, Dunnett, Stephen B., Grealish, Shane, Perlmann, Thomas, Parmar, Malin
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Clinical Progress
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222722/
https://ncbi.nlm.nih.gov/pubmed/28094017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.09.004
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