Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease

Stem cell treatments for neurodegenerative diseases are expected to reach clinical trials soon. Most of the approaches currently under development involve transplantation of immature progenitors that subsequently undergo phenotypic and functional maturation in vivo, and predicting the long-term graf...

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Bibliographic Details
Published in:Cell Stem Cell
Main Authors: Kirkeby, Agnete, Nolbrant, Sara, Tiklova, Katarina, Heuer, Andreas, Kee, Nigel, Cardoso, Tiago, Ottosson, Daniella Rylander, Lelos, Mariah J., Rifes, Pedro, Dunnett, Stephen B., Grealish, Shane, Perlmann, Thomas, Parmar, Malin
Format: Artigo
Language:Inglês
Published: Cell Press 2017
Subjects:
Clinical Progress
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222722/
https://ncbi.nlm.nih.gov/pubmed/28094017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.09.004
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