Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of parkinsonian rats

Dopamine (DA) neurons derived from human embryonic stem cells (hESCs) are a promising unlimited source of cells for cell replacement therapy in Parkinson's disease (PD). A number of studies have demonstrated functionality of DA neurons originating from hESCs when grafted to the striatum of rode...

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Bibliografske podrobnosti
izdano v:J Comp Neurol
Main Authors: Cardoso, Tiago, Adler, Andrew F., Mattsson, Bengt, Hoban, Deirdre B., Nolbrant, Sara, Wahlestedt, Jenny Nelander, Kirkeby, Agnete, Grealish, Shane, Björklund, Anders, Parmar, Malin
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2018
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175216/
https://ncbi.nlm.nih.gov/pubmed/30007046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.24500
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