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ADGRE1 (EMR1, F4/80) Is a Rapidly-Evolving Gene Expressed in Mammalian Monocyte-Macrophages

The F4/80 antigen, encoded by the Adgre1 locus, has been widely-used as a monocyte-macrophage marker in mice, but its value as a macrophage marker in other species is unclear, and has even been questioned. ADGRE1 is a seven transmembrane G protein-coupled receptor with an extracellular domain contai...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Waddell, Lindsey A., Lefevre, Lucas, Bush, Stephen J., Raper, Anna, Young, Rachel, Lisowski, Zofia M., McCulloch, Mary E. B., Muriuki, Charity, Sauter, Kristin A., Clark, Emily L., Irvine, Katharine M., Pridans, Clare, Hope, Jayne C., Hume, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174849/
https://ncbi.nlm.nih.gov/pubmed/30327653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02246
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