Species-Specificity of Transcriptional Regulation and the Response to Lipopolysaccharide in Mammalian Macrophages

Mammalian macrophages differ in their basal gene expression profiles and response to the toll-like receptor 4 (TLR4) agonist, lipopolysaccharide (LPS). In human macrophages, LPS elicits a temporal cascade of transient gene expression including feed forward activators and feedback regulators that lim...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Bush, Stephen J., McCulloch, Mary E. B., Lisowski, Zofia M., Muriuki, Charity, Clark, Emily L., Young, Rachel, Pridans, Clare, Prendergast, James G. D., Summers, Kim M., Hume, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386301/
https://ncbi.nlm.nih.gov/pubmed/32793601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00661
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