Protein Modification by Endogenously Generated Lipid Electrophiles: Mitochondria as the Source and Target

Determining the impact of lipid electrophile-mediated protein damage that occurs during oxidative stress requires a comprehensive analysis of electrophile targets adducted under pathophysiological conditions. Incorporation of ω-alkynyl linoleic acid into the phospholipids of macrophages prior to act...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Beavers, William N., Rose, Kristie L., Galligan, James J., Mitchener, Michelle M., Rouzer, Carol A., Tallman, Keri A., Lamberson, Connor R., Wang, Xiaojing, Hill, Salisha, Ivanova, Pavlina T., Alex Brown, H., Zhang, Bing, Porter, Ned A., Marnett, Lawrence J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174696/
https://ncbi.nlm.nih.gov/pubmed/28613820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00480
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