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Protein Modification by Endogenously Generated Lipid Electrophiles: Mitochondria as the Source and Target

Determining the impact of lipid electrophile-mediated protein damage that occurs during oxidative stress requires a comprehensive analysis of electrophile targets adducted under pathophysiological conditions. Incorporation of ω-alkynyl linoleic acid into the phospholipids of macrophages prior to act...

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Publicado en:ACS Chem Biol
Main Authors: Beavers, William N., Rose, Kristie L., Galligan, James J., Mitchener, Michelle M., Rouzer, Carol A., Tallman, Keri A., Lamberson, Connor R., Wang, Xiaojing, Hill, Salisha, Ivanova, Pavlina T., Alex Brown, H., Zhang, Bing, Porter, Ned A., Marnett, Lawrence J.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174696/
https://ncbi.nlm.nih.gov/pubmed/28613820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00480
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