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Antiestrogen- and tamoxifen-induced effects on calcium-activated chloride currents in epithelial cells carrying the ∆F508-CFTR point mutation

BACKGROUND: Although pharmacological treatment has increased the average life expectancy of patients with cystic fibrosis, the median survival of females is shorter than that of males. In vitro and in vivo studies have shown that estrogens play a relevant role in the disease progression. The aim of...

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書誌詳細
出版年:Respir Res
主要な著者: Imberti, Roberto, Garavaglia, Maria Lisa, Verduci, Ivan, Cannavale, Gaetano, Balduzzi, Giorgio, Papetti, Sara, Mazzanti, Michele
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173901/
https://ncbi.nlm.nih.gov/pubmed/30290809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0901-1
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