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Antiestrogen- and tamoxifen-induced effects on calcium-activated chloride currents in epithelial cells carrying the ∆F508-CFTR point mutation

BACKGROUND: Although pharmacological treatment has increased the average life expectancy of patients with cystic fibrosis, the median survival of females is shorter than that of males. In vitro and in vivo studies have shown that estrogens play a relevant role in the disease progression. The aim of...

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Pubblicato in:Respir Res
Autori principali: Imberti, Roberto, Garavaglia, Maria Lisa, Verduci, Ivan, Cannavale, Gaetano, Balduzzi, Giorgio, Papetti, Sara, Mazzanti, Michele
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173901/
https://ncbi.nlm.nih.gov/pubmed/30290809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0901-1
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