Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion

Interleukin 25 (IL-25) is a major 'alarmin' cytokine, capable of initiating and amplifying the type immune response to helminth parasites. However, its role in the later effector phase of clearing chronic infection remains unclear. The helminth Heligmosomoides polygyrus establishes long-te...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Smith, Katherine A, Löser, Stephan, Varyani, Fumi, Harcus, Yvonne, McSorley, Henry J, McKenzie, Andrew NJ, Maizels, Rick M
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2018
Teme:
Immunology and Inflammation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173579/
https://ncbi.nlm.nih.gov/pubmed/30238872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38269
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