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Berenil Binds Tightly to Parallel and Mixed Parallel/Antiparallel G-Quadruplex Motifs with Varied Thermodynamic Signatures
[Image: see text] Diminazene, DMZ, (or berenil) has been reported as a tight binder of G-quadruplexes. G-Quadruplex structures are often located in the promotor regions of oncogenes and may play a regulatory role in gene expression based on the stability of the folding topology. In this study, attem...
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| Publicat a: | ACS Omega |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical Society
2018
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6173502/ https://ncbi.nlm.nih.gov/pubmed/30320266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01621 |
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