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Compound C inhibits nonsense-mediated RNA decay independently of AMPK

The nonsense mediated RNA decay (NMD) pathway safeguards the integrity of the transcriptome by targeting mRNAs with premature translation termination codons (PTCs) for degradation. It also regulates gene expression by degrading a large number of non-mutant RNAs (including mRNAs and noncoding RNAs) t...

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Vydáno v:PLoS One
Hlavní autoři: Cheruiyot, Abigael, Li, Shan, Nickless, Andrew, Roth, Robyn, Fitzpatrick, James A. J., You, Zhongsheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173407/
https://ncbi.nlm.nih.gov/pubmed/30289931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204978
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