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Control of gene expression through the nonsense-mediated RNA decay pathway
Nonsense-mediated RNA decay (NMD) was originally discovered as a cellular surveillance pathway that safeguards the quality of mRNA transcripts in eukaryotic cells. In its canonical function, NMD prevents translation of mutant mRNAs harboring premature termination codons (PTCs) by targeting them for...
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| Publicado no: | Cell Biosci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5437625/ https://ncbi.nlm.nih.gov/pubmed/28533900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-017-0153-7 |
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