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Compound C inhibits nonsense-mediated RNA decay independently of AMPK
The nonsense mediated RNA decay (NMD) pathway safeguards the integrity of the transcriptome by targeting mRNAs with premature translation termination codons (PTCs) for degradation. It also regulates gene expression by degrading a large number of non-mutant RNAs (including mRNAs and noncoding RNAs) t...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6173407/ https://ncbi.nlm.nih.gov/pubmed/30289931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204978 |
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