A novel RGDyC/PEG co-modified PAMAM dendrimer-loaded arsenic trioxide of glioma targeting delivery system

BACKGROUND: The Traditional Chinese Medicine, arsenic trioxide (ATO, As(2)O(3)) could inhibit growth and induce apoptosis in a variety of solid tumor cells, but it is severely limited in the treatment of glioma due to its poor BBB penetration and nonspecifcity distribution in vivo. PURPOSE: The obje...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Lu, Yanping, Han, Shunping, Zheng, Hongyue, Ma, Rui, Ping, Yuting, Zou, Jiafeng, Tang, Hongxia, Zhang, Yongping, Xu, Xiuling, Li, Fanzhu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173183/
https://ncbi.nlm.nih.gov/pubmed/30323584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S175418
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