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Injectable PAMAM dendrimer-PEG hydrogels for the treatment of genital infections: formulation, in-vitro and in-vivo evaluation

Local intravaginal drug therapy is preferred for treatment of ascending genital infections during pregnancy. In the present study, in-situ forming biodegradable hydrogel for sustained release of amoxicillin in the cervicovaginal region is described. A generation 4 poly(amidoamine) [G4-(NH(2))(64)] d...

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Detalhes bibliográficos
Main Authors: Navath, Raghavendra S., Menjoge, Anupa R., Dai, Hui, Romero, Roberto, Kannan, Sujatha, Kannan, Rangaramanujam M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556449/
https://ncbi.nlm.nih.gov/pubmed/21615144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200027z
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