Inhibition of Bacterial Growth and Intramniotic Infection in a Guinea Pig Model of Chorioamnionitis Using PAMAM Dendrimers

Dendrimers have emerged as topical microbicides to treat vaginal infections. This study explores the in-vitro, in-vivo antimicrobial activity of PAMAM dendrimers, and the associated mechanism. Interestingly, topical cervical application of 500 µg of generation-4 neutral dendrimer (G(4)-PAMAM-OH) sho...

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Detalhes bibliográficos
Main Authors: Wang, Bing, Navath, Raghavendra S., Menjoge, Anupa R., Balakrishnan, Bindu, Bellair, Robert, Dai, Hui, Romero, Roberto, Kannan, Sujatha, Kannan, Rangaramanujam M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908334/
https://ncbi.nlm.nih.gov/pubmed/20580797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2010.05.030
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