Liposomal formulations of carboplatin injected by convection-enhanced delivery increases the median survival time of F98 glioma bearing rats

BACKGROUND: Effectiveness of chemotherapy for treating glioblastoma (GBM) brain tumors is hampered by the blood–brain barrier which limits the entry into the brain of most drugs from the blood. To bypass this barrier, convection-enhanced delivery (CED) was proposed to directly inject drugs in tumor....

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: Shi, Minghan, Anantha, Malathi, Wehbe, Mohamed, Bally, Marcel B., Fortin, David, Roy, Laurent-Olivier, Charest, Gabriel, Richer, Maxime, Paquette, Benoit, Sanche, Léon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172733/
https://ncbi.nlm.nih.gov/pubmed/30290821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0404-8
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