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Convection-enhancement delivery of platinum-based drugs and Lipoplatin(™) to optimize the concomitant effect with radiotherapy in F98 glioma rat model

The prognosis for patients with glioblastoma remains poor with current treatments. Although platinum based drugs are sometimes offered at relapse, their efficacy in this setting is still disputed. In this study, we use convection-enhanced delivery (CED) to deliver the platinum-based drugs (cisplatin...

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Detalhes bibliográficos
Publicado no:Invest New Drugs
Main Authors: Shi, Minghan, Fortin, David, Sanche, Léon, Paquette, Benoit
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623750/
https://ncbi.nlm.nih.gov/pubmed/25784204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-015-0228-4
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