Liposomal formulations of carboplatin injected by convection-enhanced delivery increases the median survival time of F98 glioma bearing rats

BACKGROUND: Effectiveness of chemotherapy for treating glioblastoma (GBM) brain tumors is hampered by the blood–brain barrier which limits the entry into the brain of most drugs from the blood. To bypass this barrier, convection-enhanced delivery (CED) was proposed to directly inject drugs in tumor....

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Dettagli Bibliografici
Pubblicato in:J Nanobiotechnology
Autori principali: Shi, Minghan, Anantha, Malathi, Wehbe, Mohamed, Bally, Marcel B., Fortin, David, Roy, Laurent-Olivier, Charest, Gabriel, Richer, Maxime, Paquette, Benoit, Sanche, Léon
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172733/
https://ncbi.nlm.nih.gov/pubmed/30290821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0404-8
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