Liposomal formulations of carboplatin injected by convection-enhanced delivery increases the median survival time of F98 glioma bearing rats

BACKGROUND: Effectiveness of chemotherapy for treating glioblastoma (GBM) brain tumors is hampered by the blood–brain barrier which limits the entry into the brain of most drugs from the blood. To bypass this barrier, convection-enhanced delivery (CED) was proposed to directly inject drugs in tumor....

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Dades bibliogràfiques
Publicat a:J Nanobiotechnology
Autors principals: Shi, Minghan, Anantha, Malathi, Wehbe, Mohamed, Bally, Marcel B., Fortin, David, Roy, Laurent-Olivier, Charest, Gabriel, Richer, Maxime, Paquette, Benoit, Sanche, Léon
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172733/
https://ncbi.nlm.nih.gov/pubmed/30290821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0404-8
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