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Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity

As a potent chemotherapy drug, cisplatin is also notorious for its side-effects including nephrotoxicity in kidneys, presenting a pressing need to identify renoprotective agents. Cisplatin nephrotoxicity involves epigenetic regulations, including changes in histone acetylation. Bromodomain and extra...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Sun, Liping, Liu, Jing, Yuan, Yanggang, Zhang, Xinzhou, Dong, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172575/
https://ncbi.nlm.nih.gov/pubmed/29767555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00527.2017
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