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Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity
As a potent chemotherapy drug, cisplatin is also notorious for its side-effects including nephrotoxicity in kidneys, presenting a pressing need to identify renoprotective agents. Cisplatin nephrotoxicity involves epigenetic regulations, including changes in histone acetylation. Bromodomain and extra...
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| Publicat a: | Am J Physiol Renal Physiol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6172575/ https://ncbi.nlm.nih.gov/pubmed/29767555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00527.2017 |
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