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Epigenetic Blockade of Neoplastic Transformation by Bromodomain and Extra-Terminal (BET) Domain Protein Inhibitor JQ-1

The neoplastic transformation of cells and inflammation are processes that contribute to tumor initiation. Recently, emerging evidence has suggested that epigenetic alterations are also implicated in the early stages of carcinogenesis. Therefore, potent small molecules targeting epigenetic regulator...

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Publicat a:Biochem Pharmacol
Autors principals: Zhang, Chengyue, Su, Zheng-Yuan, Wang, Ling, Shu, Limin, Yang, Yuqing, Guo, Yue, Pung, Douglas, Bountra, Chas, Kong, Ah-Ng
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031540/
https://ncbi.nlm.nih.gov/pubmed/27520485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.08.009
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