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Epigenetic Blockade of Neoplastic Transformation by Bromodomain and Extra-Terminal (BET) Domain Protein Inhibitor JQ-1

The neoplastic transformation of cells and inflammation are processes that contribute to tumor initiation. Recently, emerging evidence has suggested that epigenetic alterations are also implicated in the early stages of carcinogenesis. Therefore, potent small molecules targeting epigenetic regulator...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Zhang, Chengyue, Su, Zheng-Yuan, Wang, Ling, Shu, Limin, Yang, Yuqing, Guo, Yue, Pung, Douglas, Bountra, Chas, Kong, Ah-Ng
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031540/
https://ncbi.nlm.nih.gov/pubmed/27520485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.08.009
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