Epigenetic Blockade of Neoplastic Transformation by Bromodomain and Extra-Terminal (BET) Domain Protein Inhibitor JQ-1

The neoplastic transformation of cells and inflammation are processes that contribute to tumor initiation. Recently, emerging evidence has suggested that epigenetic alterations are also implicated in the early stages of carcinogenesis. Therefore, potent small molecules targeting epigenetic regulator...

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Pubblicato in:Biochem Pharmacol
Autori principali: Zhang, Chengyue, Su, Zheng-Yuan, Wang, Ling, Shu, Limin, Yang, Yuqing, Guo, Yue, Pung, Douglas, Bountra, Chas, Kong, Ah-Ng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031540/
https://ncbi.nlm.nih.gov/pubmed/27520485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.08.009
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