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Canagliflozin reduces cisplatin uptake and activates Akt to protect against cisplatin-induced nephrotoxicity

Cisplatin is a widely used chemotherapy drug with notorious nephrotoxicity. Na(+)-glucose cotransporter 2 inhibitors are a class of novel antidiabetic agents that may have other effects in the kidneys besides blood glucose control. In the present study, we demonstrated that canagliflozin significant...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Renal Physiol
Hoofdauteurs: Song, Zhixia, Zhu, Jiefu, Wei, Qingqing, Dong, Guie, Dong, Zheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191450/
https://ncbi.nlm.nih.gov/pubmed/32150448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00512.2019
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