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Activation and involvement of p53 in cisplatin-induced nephrotoxicity

Cisplatin, a widely used chemotherapy drug, induces acute kidney injury, which limits its use and efficacy in cancer treatment. However, the molecular mechanism of cisplatin-induced nephrotoxicity is currently unclear. Using pharmacological and gene knockout models, we now demonstrate a pathological...

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Bibliografische gegevens
Hoofdauteurs: Wei, Qingqing, Dong, Guie, Yang, Tianxin, Megyesi, Judit, Price, Peter M., Dong, Zheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792752/
https://ncbi.nlm.nih.gov/pubmed/17670903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00230.2007
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