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Activation and involvement of p53 in cisplatin-induced nephrotoxicity
Cisplatin, a widely used chemotherapy drug, induces acute kidney injury, which limits its use and efficacy in cancer treatment. However, the molecular mechanism of cisplatin-induced nephrotoxicity is currently unclear. Using pharmacological and gene knockout models, we now demonstrate a pathological...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2792752/ https://ncbi.nlm.nih.gov/pubmed/17670903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00230.2007 |
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