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Collecting duct principal, but not intercalated, cell prorenin receptor regulates renal sodium and water excretion

The collecting duct is the predominant nephron site of prorenin and prorenin receptor (PRR) expression. We previously demonstrated that the collecting duct PRR regulates epithelial Na(+) channel (ENaC) activity and water transport; however, which cell type is involved remains unclear. Herein, we exa...

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Bibliografske podrobnosti
izdano v:Am J Physiol Renal Physiol
Main Authors: Ramkumar, Nirupama, Stuart, Deborah, Mironova, Elena, Abraham, Nikita, Gao, Yang, Wang, Shuping, Lakshmipathi, Jayalakshmi, Stockand, James D., Kohan, Donald E.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2018
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172572/
https://ncbi.nlm.nih.gov/pubmed/29790390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00122.2018
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