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Collecting duct principal, but not intercalated, cell prorenin receptor regulates renal sodium and water excretion

The collecting duct is the predominant nephron site of prorenin and prorenin receptor (PRR) expression. We previously demonstrated that the collecting duct PRR regulates epithelial Na(+) channel (ENaC) activity and water transport; however, which cell type is involved remains unclear. Herein, we exa...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Ramkumar, Nirupama, Stuart, Deborah, Mironova, Elena, Abraham, Nikita, Gao, Yang, Wang, Shuping, Lakshmipathi, Jayalakshmi, Stockand, James D., Kohan, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172572/
https://ncbi.nlm.nih.gov/pubmed/29790390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00122.2018
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