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Renal tubular epithelial cell prorenin receptor regulates blood pressure and sodium transport

The physiological significance of the renal tubular prorenin receptor (PRR) has been difficult to elucidate due to developmental abnormalities associated with global or renal-specific PRR knockout (KO). We recently developed an inducible renal tubule-wide PRR KO using the Pax8/LC1 transgenes and dem...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Ramkumar, Nirupama, Stuart, Deborah, Mironova, Elena, Bugay, Vladislav, Wang, Shuping, Abraham, Nikita, Ichihara, Atsuhiro, Stockand, James D., Kohan, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967157/
https://ncbi.nlm.nih.gov/pubmed/27053687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00088.2016
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