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Renal tubular epithelial cell prorenin receptor regulates blood pressure and sodium transport

The physiological significance of the renal tubular prorenin receptor (PRR) has been difficult to elucidate due to developmental abnormalities associated with global or renal-specific PRR knockout (KO). We recently developed an inducible renal tubule-wide PRR KO using the Pax8/LC1 transgenes and dem...

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Détails bibliographiques
Publié dans:Am J Physiol Renal Physiol
Auteurs principaux: Ramkumar, Nirupama, Stuart, Deborah, Mironova, Elena, Bugay, Vladislav, Wang, Shuping, Abraham, Nikita, Ichihara, Atsuhiro, Stockand, James D., Kohan, Donald E.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967157/
https://ncbi.nlm.nih.gov/pubmed/27053687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00088.2016
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