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Lack of an effect of collecting duct-specific deletion of adenylyl cyclase 3 on renal Na(+) and water excretion or arterial pressure

cAMP is a key mediator of connecting tubule and collecting duct (CD) Na(+) and water reabsorption. Studies performed in vitro have suggested that CD adenylyl cyclase (AC)3 partly mediates the actions of vasopressin; however, the physiological role of CD AC3 has not been determined. To assess this, m...

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Detalhes bibliográficos
Main Authors: Kittikulsuth, Wararat, Stuart, Deborah, Van Hoek, Alfred N., Stockand, James D., Bugaj, Vladislav, Mironova, Elena, Blount, Mitsi A., Kohan, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949037/
https://ncbi.nlm.nih.gov/pubmed/24431204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00505.2013
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