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Lack of an effect of nephron-specific deletion of adenylyl cyclase 3 on renal sodium and water excretion or arterial pressure

Adenylyl cyclase (AC)-stimulated cAMP plays a key role in modulating transport and channel activity along the nephron. However, the role of individual adenylyl cyclase isoforms in such regulation is largely unknown. Since adenylyl cyclase 3 (AC3) is expressed throughout nephron, we investigated its...

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Pubblicato in:Physiol Rep
Autori principali: Kittikulsuth, Wararat, Stuart, Deborah, Van Hoek, Alfred N, Kohan, Donald E
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393152/
https://ncbi.nlm.nih.gov/pubmed/25747587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12316
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