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A Novel Aurora-A Inhibitor (MLN8237) Synergistically Enhances the Antitumor Activity of Sorafenib in Hepatocellular Carcinoma

Currently, sorafenib-based therapy is the standard treatment for advanced hepatocellular carcinoma (HCC), and there is a strong rationale for investigating its use in combination with other agents to achieve better therapeutic effects. Aurora-A, a member of a family of mitotic serine/threonine kinas...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Zhang, Kai, Wang, Ting, Zhou, Hao, Feng, Bing, Chen, Ying, Zhi, Yingru, Wang, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172479/
https://ncbi.nlm.nih.gov/pubmed/30292139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.08.014
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