Aurora Inhibitor MLN8237 in Combination with Docetaxel Enhances Apoptosis and Antitumor Activity in Mantle Cell Lymphoma

Auroras (A and B) are oncogenic serine/threonine kinases that play key roles in the mitotic phase of the eukaryotic cell cycle. Analysis of the Leukemia Lymphoma Molecular Profiling Project (LLMPP) database indicates Aurora over-expression correlates with poor prognosis. A tissue microarray (TMA) co...

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Hoofdauteurs: Qi, Wenqing, Cooke, Laurence S., Liu, Xiaobing, Rimsza, Lisa, Roe, Denise J., Manziolli, Ann, Persky, Daniel O., Miller, Thomas P., Mahadevan, Daruka
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792566/
https://ncbi.nlm.nih.gov/pubmed/21291867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.01.017
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