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MLN-8237: A dual inhibitor of aurora A and B in soft tissue sarcomas

Aurora kinases have become an attractive target in cancer therapy due to their deregulated expression in human tumors. Liposarcoma, a type of soft tissue sarcoma in adults, account for approximately 20% of all adult soft tissue sarcomas. There are no effective chemotherapies for majority of these tu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nair, Jayasree S., Schwartz, Gary K.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914329/
https://ncbi.nlm.nih.gov/pubmed/26887042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7335
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