MEG3 is increased in idiopathic pulmonary fibrosis and regulates epithelial cell differentiation

Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease causing fibrotic remodeling of the peripheral lung, leading to respiratory failure. Peripheral pulmonary epithelial cells lose normal alveolar epithelial gene expression patterns and variably express genes associated with div...

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Pubblicato in:JCI Insight
Autori principali: Gokey, Jason J., Snowball, John, Sridharan, Anusha, Speth, Joseph P., Black, Katharine E., Hariri, Lida P., Perl, Anne-Karina T., Xu, Yan, Whitsett, Jeffrey A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171798/
https://ncbi.nlm.nih.gov/pubmed/30185671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122490
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