MEG3 is increased in idiopathic pulmonary fibrosis and regulates epithelial cell differentiation

Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease causing fibrotic remodeling of the peripheral lung, leading to respiratory failure. Peripheral pulmonary epithelial cells lose normal alveolar epithelial gene expression patterns and variably express genes associated with div...

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Опубликовано в: :JCI Insight
Главные авторы: Gokey, Jason J., Snowball, John, Sridharan, Anusha, Speth, Joseph P., Black, Katharine E., Hariri, Lida P., Perl, Anne-Karina T., Xu, Yan, Whitsett, Jeffrey A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171798/
https://ncbi.nlm.nih.gov/pubmed/30185671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122490
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