Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a lethal interstitial lung disease characterized by airway remodeling, inflammation, alveolar destruction, and fibrosis. We utilized single-cell RNA sequencing (scRNA-seq) to identify epithelial cell types and associated biological processes involved in the pat...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Xu, Yan, Mizuno, Takako, Sridharan, Anusha, Du, Yina, Guo, Minzhe, Tang, Jie, Wikenheiser-Brokamp, Kathryn A., Perl, Anne-Karina T., Funari, Vincent A., Gokey, Jason J., Stripp, Barry R., Whitsett, Jeffrey A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135277/
https://ncbi.nlm.nih.gov/pubmed/27942595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90558
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